null

SMILES Cc1ccc(NC(=O)c2ccoc2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key InChIKey=HNOVOESCCUJDRT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50262865   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human recombinant p38alpha-mediated ATF2 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3M0BPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3M0BPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5T5PPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5T5PPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of p38alpha phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3M0BPubMed
TargetHeat shock protein beta-1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50262865(CHEMBL477583 | Furan-3-carboxylic acid [4'-(cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3M0BPubMed