null
SMILES FC(F)(F)c1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(cnc45)C(=O)NCc4ccc(cc4)C(F)(F)F)cccc3c2)cc1
InChI Key InChIKey=FPVOUNLVCWCJTP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50264416
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair
TargetSTAM-binding protein(Homo sapiens (Human))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assayMore data for this Ligand-Target Pair
Target26S proteasome non-ATPase regulatory subunit 14(Homo sapiens (Human))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76...More data for this Ligand-Target Pair
TargetCOP9 signalosome complex subunit 5(Homo sapiens (Human))
University of California San Diego
Curated by ChEMBL
University of California San Diego
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair