null
SMILES Cc1ccc(cc1-c1ccc2c(noc2c1)C1CCNCC1)C(=O)Nc1cccc(c1)N1CCOCC1
InChI Key InChIKey=UVUGBBNUQBSROH-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50264755
Affinity DataKi: 1.40nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of MEK1 by cRaf/mek/Erk cascade assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair