null

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(c2)-c2ccc(cc2)-c2csc(N)n2)CC1

InChI Key InChIKey=BGOWMSRXCRUANU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50264990   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataKi: >850nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50264990(CHEMBL496129 | N-(4'-(2-aminothiazol-4-yl)-6-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMed