null
SMILES Cc1nnc(o1)-c1ccc(c(C)c1)-c1cc(ccc1C)C(=O)NC1CC1
InChI Key InChIKey=UBVTVSINEVHYSY-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50265033
Affinity DataKi: 10nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q28K7B0RPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataKi: 10nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2J38WW2PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2J38WW2PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of cFMSMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of SGK1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MEK1 by cRaf/mek/Erk cascade assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ErbB4More data for this Ligand-Target Pair