null

SMILES CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(c1)-c1cn(C)c(=O)cc1OC

InChI Key InChIKey=VQLUIPPOGYKKSA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265627   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265627(CHEMBL4099335)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM50265627(CHEMBL4099335)copy SMILEScopy InChI
Affinity DataEC50:  56nMAssay Description:Inhibition of BRD4 in human NCI-H1299 cells after 24 hrs by Bright-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8VPNPubMed