null

SMILES FC(F)(F)Cn1c(cc2cc(ccc12)C(=O)N1CCN(CC1)C1CCC1)C(=O)N1CCOCC1

InChI Key InChIKey=JYHISTRLDOWQMN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268452   

TargetHistamine H3 receptor(Rattus norvegicus (rat))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50268452((4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbo...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB46NQPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50268452((4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbo...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from human recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB46NQPubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by ChEMBL
LigandPNGBDBM50268452((4-cyclobutylpiperazin-1-yl)(2-(morpholine-4-carbo...)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Inverse agonist activity at human histamine H3 receptor expressed in CHO cells by GTPgamma[35S] binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB46NQPubMed