null

SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCN(CC1)C(=O)CCOCCOCCOCCONC(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)N1CCOCC1

InChI Key InChIKey=XIUWBGIKSXLESW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50271205   

LigandPNGBDBM50271205(CHEMBL4127114)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110alpha/p85alpha expressed in baculovirus expression system coexpressing PIK3R1 by TR-F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0J00PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271205(CHEMBL4127114)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human GST-tagged MEK1 expressed in baculovirus infected Sf9 insect cells using inactive ERK2 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0J00PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271205(CHEMBL4127114)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110gamma expressed in baculovirus expression system by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0J00PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271205(CHEMBL4127114)copy SMILEScopy InChI
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0J00PubMed
LigandPNGBDBM50271205(CHEMBL4127114)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110delta/p85alpha expressed in baculovirus expression system coexpressing PIK3R1 by TR-F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0J00PubMed