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SMILES Cc1cc(ccc1O)-c1cc(nc(=O)[nH]1)-c1ccccc1

InChI Key InChIKey=MHPMAOLCNNEBOA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272192   

TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of CDC7-DBF4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319VPMPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)copy SMILEScopy InChI
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NNFPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)copy SMILEScopy InChI
Affinity DataIC50: 332nMAssay Description:Inhibition of N-terminus His-tagged human PIM1 expressed in Escherichia coli using AKRRRLSA as substrate after 1 to 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4WS0PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NNFPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of N-terminus Myc-tagged human CDC7 expressed in Escherichia coli by chemiluminescence assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4WS0PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)copy SMILEScopy InChI
Affinity DataIC50: 17.2nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NNFPubMed