null

SMILES Cc1ccccc1O[C@@H]1[C@H](CN)OCc2ccccc12

InChI Key InChIKey=BHTUHPLMWNGSLY-IRXDYDNUSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50272688   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NP8PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NP8PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5NP8PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant CYP32D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H8VPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H8VPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H8VPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences, Inc.

Curated by ChEMBL
LigandPNGBDBM50272688(((3S,4S)-4-(o-tolyloxy)-3,4-dihydro-1H-isochromen-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H8VPubMed