null

SMILES C[C@H](NC1=NC(=O)C(C)(S1)c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=MIGKHDFDKUOWGG-FAQQKDIKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50273822   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50273822(5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethyla...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GN7PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50273822(5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethyla...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GN7PubMed