null

SMILES CCC(=O)Nc1ccc(Sc2nc(Nc3cc(C)n[nH]3)cc(n2)N2CCN(C)CC2)cc1

InChI Key InChIKey=LCQYMDMUCJFFKN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277639   

TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL
LigandPNGBDBM50277639(CHEMBL484609 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Inhibition of Aurora-A by coupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7944PubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL
LigandPNGBDBM50277639(CHEMBL484609 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibition of Aurora-BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7944PubMed
TargetAurora kinase A(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL
LigandPNGBDBM50277639(CHEMBL484609 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of aurora A kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85920PubMed
TargetAurora kinase B(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd

Curated by ChEMBL
LigandPNGBDBM50277639(CHEMBL484609 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of aurora B kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85920PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People's Hospital of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50277639(CHEMBL484609 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...)copy SMILEScopy InChI
Affinity DataIC50: 603nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TMDPubMed