null

SMILES O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1

InChI Key InChIKey=KINMYBBFQRSVLL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50279106   

TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of cloned Kv1.3 channel (unknown origin) expressed in mammalian cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4B38PubMed
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cloned IK1 expressed in african green monkey COS7 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4B38PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 potassium channel expressed in mouse L929 cells by whole cell patch clampMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4X5NPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of human Kv1.3 ion channel expressed in CGE22 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VW2PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibition of human Kv1.5 ion channel expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VW2PubMed
TargetPotassium voltage-gated channel subfamily A member 2(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of human Kv1.2 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668GT4PubMed
TargetPotassium voltage-gated channel subfamily A member 1(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human Kv1.1 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668GT4PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668GT4PubMed
TargetPotassium voltage-gated channel subfamily A member 4(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668GT4PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668GT4PubMed
TargetPotassium voltage-gated channel subfamily A member 6(Homo sapiens (Human))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668GT4PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50279106(4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one | ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4JXWPubMed