null

SMILES Cc1ccn2nc(O)c(C(=O)Nc3c(F)c(F)c(-c4ccccc4)c(F)c3F)c2c1

InChI Key InChIKey=ZBLNACULOGDXAT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50281171   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli BL21(DE3) assessed as inhibition of DC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X5BBPPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate preincubated for 5...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164QNPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University of Turin

Curated by ChEMBL
LigandPNGBDBM50281171(CHEMBL4177202 | US20240034730, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
In DepthDetails