null
SMILES COc1cc2c(NC3CCN(CC3)C3CC3)cc(nc2cc1OCCCN1CCCC1)-c1ccc(C)o1
InChI Key InChIKey=BIJYNDLTSDYKHJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50281308
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universidad de Oviedo-Principado de Asturias
Curated by ChEMBL
Universidad de Oviedo-Principado de Asturias
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Universidad de Oviedo-Principado de Asturias
Curated by ChEMBL
Universidad de Oviedo-Principado de Asturias
Curated by ChEMBL
Affinity DataIC50: 413nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Universidad de Oviedo-Principado de Asturias
Curated by ChEMBL
Universidad de Oviedo-Principado de Asturias
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human GLP using histone H3 peptide as substrate after 120 mins in presence of [3H]SAM by radiometric assayMore data for this Ligand-Target Pair