null

SMILES CS(=O)(=O)c1ccc(cc1)-c1csc(Br)c1-c1ccc(F)cc1

InChI Key InChIKey=FJVLFULBBXMDBS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50286048   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286048(2-Bromo-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibitory activity against human recombinant Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58D2
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50286048(2-Bromo-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 1 expressed in microsomes taken from baculovirus infected Sf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4VR4
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50286048(2-Bromo-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human COX-2 expressed in Baculovirus infected sf9 cells using arachidonic acid as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7DSWPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50286048(2-Bromo-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity of the compound against human recombinant Prostaglandin G/H synthase 2 expressed in microsomes taken from baculovirus infected Sf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4VR4
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50286048(2-Bromo-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7DSWPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50286048(2-Bromo-3-(4-fluoro-phenyl)-4-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against human recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM58D2