null

SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(Nc3nccc(n3)-c3cccnc3)c2)CC1

InChI Key InChIKey=JHMBUEWQJDGKGS-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50290422   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel, Inc.

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ88RCPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People's Hospital of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6TMDPubMed
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
TargetBreakpoint cluster region protein(Mus musculus)TBA
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))TBA
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
In DepthDetails
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 4.75E+5nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X86MF