null
SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cccc(Nc3nccc(n3)-c3cccnc3)c2)CC1
InChI Key InChIKey=JHMBUEWQJDGKGS-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50290422
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People's Hospital of Hangzhou
Curated by ChEMBL
The First People's Hospital of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 200nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
In DepthDetails
In DepthDetails
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 4.75E+5nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair