null

SMILES CNc1nc2[nH]c(cc2c2n(C)cnc12)-c1cccc(CNC(C)=O)c1

InChI Key InChIKey=YDGFHFMRNSUOFT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294682   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50294682(CHEMBL552183 | N-(3-(1-methyl-4-(methylamino)-1,6-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of IKK1-catalyzed phosphorylation of GST-tagged IkappaBalpha fusion protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SX8PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50294682(CHEMBL552183 | N-(3-(1-methyl-4-(methylamino)-1,6-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SHGPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50294682(CHEMBL552183 | N-(3-(1-methyl-4-(methylamino)-1,6-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human IKK2-mediated GST-IkappaBalpha protein fusion phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z038KCPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50294682(CHEMBL552183 | N-(3-(1-methyl-4-(methylamino)-1,6-...)copy SMILEScopy InChI
Affinity DataIC50: 633nMAssay Description:Inhibition of IKK2-catalyzed phosphorylation of GST-tagged IkappaBalpha fusion protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SX8PubMed