null

SMILES OC(=O)c1ccc(cc1)-c1c[nH]c2ncc(cc12)-c1ccccc1

InChI Key InChIKey=KSFDVNIKNYXUIP-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296003   

TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of SGK1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2DFBPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
OriBase Pharma

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human His-tagged AXL expressed in insect cells after 60 mins by Z'-LYTE assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M96S8PubMed
TargetSerine/threonine-protein kinase Sgk1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296003(4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic ...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of SGK1-mediated epithelial sodium channel activity in human M-1 cells assessed as short circuit current by whole cell electrophysiologica...More data for this Ligand-Target Pair