null

SMILES COc1ccc(cc1OCCO)C(=O)Nc1ncc(Cc2ccc(F)c(Cl)c2)s1

InChI Key InChIKey=IXAHGCSQQMXJED-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296529   

TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50296529(CHEMBL552270 | N-(5-(3-chloro-4-fluorobenzyl)thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of SCD1 in mouse microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836H1PubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50296529(CHEMBL552270 | N-(5-(3-chloro-4-fluorobenzyl)thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human SCD1 expressed in HEK293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836H1PubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50296529(CHEMBL552270 | N-(5-(3-chloro-4-fluorobenzyl)thiaz...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of SCD1 in human microsomes assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836H1PubMed