null

SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)c2ccccc2CC(=O)NO)cc1

InChI Key InChIKey=YOMXWXIANUYIMH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50299051   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 1 hr preincubation by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RNRPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 0.890nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 30 mins preincubation by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Universit£ di Pisa

Curated by ChEMBL
LigandPNGBDBM50299051(CHEMBL573715 | N-Hydroxy-2-{2-[4-(4-methoxy-phenox...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ3ZZSPubMed