null

SMILES CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccc(CCC(O)=O)cc1C#N

InChI Key InChIKey=BKMZXLKUUMOTKA-XMMPIXPASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50299546   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of beta2 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 0.0220nMAssay Description:Displacement of [3H](2-(2-hydroxyphenyl)-6-methyl-5-(2-methylpropyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone) from human calcium receptor expressed in h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50299546(3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FB4PubMed