null

SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCCC1

InChI Key InChIKey=MLTCNEHPZTWJKH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50300031   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NP4PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08H1PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP4947PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+5nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08H1PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant G9a catalytic SET domain (913 to 1193 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP4947PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NP4PubMed