null

SMILES CN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key InChIKey=DZIUPOCVDSYPSY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50302042   

TargetProtein kinase C eta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of PKCeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C theta type(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of PKCbeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PKCepsilon by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PKCzeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed