null

SMILES COc1cc2c(Nc3ccc(cc3F)-c3nc4ccccc4s3)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=ZEXJBANGHOAHDZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50304194   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataEC50:  1.30E+4nMAssay Description:Inhibition of VEGFR3 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of EGFR in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of VEGFR3 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of TIE2 in human HCT116 cells by cellular phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetAurora kinase B(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 805nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetAurora kinase A(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of PDGFRbeta by microplate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed
TargetAurora kinase B(Homo sapiens (Human))
4SC AG

Curated by ChEMBL
LigandPNGBDBM50304194(CHEMBL594228 | N-[4-(Benzo[d]thiazol-2''-yl)-2-(tr...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of Aurora-B in human HCT116 cells by cellular proliferation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GWCPubMed