null

SMILES NS(=O)(=O)c1ccc(cc1)C1=C(C(=O)NC1=O)c1ccccc1

InChI Key InChIKey=LCBYKMOZFZMSHI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305810   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50305810(1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dion...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BGQPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50305810(1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dion...)copy SMILEScopy InChI
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of COX2 assessed as PGF2alpha level by EIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZQQPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50305810(1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dion...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BGQPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50305810(1H-3-(4-sulfamoylphenyl)-4-phenyl-pyrrole-2,5-dion...)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins prior to substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0BGQPubMed