null

SMILES Cc1cc(cc(n1)C(=O)NCc1ccc(F)cc1)-c1nnn(C[C@H]2CC[C@@H](CC2)C(O)=O)n1

InChI Key InChIKey=KOTGODCEORJYIF-QAQDUYKDSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50305842   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-25(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP25More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of ADAMTS4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrilysin(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-24(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP24More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP26More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetSolute carrier family 22 member 8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human OAT3 expressed in HEK cells assessed as reduction of [3H]-estrone sulfate uptake by radioactivity counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3N0FPubMed