null

SMILES Cc1cccc2OC3(CCN(CC3)c3ccc(nn3)C(=O)NCC(O)c3cccnc3)CCc12

InChI Key InChIKey=JRWYOUUHSXSYPM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306125   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306125(CHEMBL595255 | N-(2-hydroxy-2-(pyridin-3-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306125(CHEMBL595255 | N-(2-hydroxy-2-(pyridin-3-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human SCD1 expressed in human 293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306125(CHEMBL595255 | N-(2-hydroxy-2-(pyridin-3-yl)ethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed