null

SMILES FC(F)(F)c1cccc2OC3(CCN(CC3)c3ccc(NC(=O)NCc4cccnc4)nn3)CCc12

InChI Key InChIKey=MUKSRTNWEITUID-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306128   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306128(1-(pyridin-3-ylmethyl)-3-(6-(5-(trifluoromethyl)sp...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fractionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306128(1-(pyridin-3-ylmethyl)-3-(6-(5-(trifluoromethyl)sp...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of human SCD1 expressed in human 293A cells assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50306128(1-(pyridin-3-ylmethyl)-3-(6-(5-(trifluoromethyl)sp...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WBJPubMed