null

SMILES CNC[C@@H](O)[C@@H](N1CC(C)(C)c2cccc(F)c12)c1cccc(F)c1

InChI Key InChIKey=GSZTZHVFJNFRBY-MSOLQXFVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50307460   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307460((1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99VSPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307460((1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99VSPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307460((1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99VSPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50307460((1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-in...)copy SMILEScopy InChI
Affinity DataIC50: 2.28E+4nMAssay Description:Displacement of [3H]WIN35428 from human DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J99VSPubMed