null

SMILES CC(C)OC(=O)Cc1cc(-c2ccc(cc2)S(C)(=O)=O)n(c1C)-c1cccc(F)c1

InChI Key InChIKey=VKAHIULTISIANE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50308734   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ La Sapienza

Curated by ChEMBL
LigandPNGBDBM50308734(CHEMBL589812 | Isopropyl-2-methyl-5-[4-(methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as thromboxane B2 production by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X291DPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£ La Sapienza

Curated by ChEMBL
LigandPNGBDBM50308734(CHEMBL589812 | Isopropyl-2-methyl-5-[4-(methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 10 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X291DPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£ La Sapienza

Curated by ChEMBL
LigandPNGBDBM50308734(CHEMBL589812 | Isopropyl-2-methyl-5-[4-(methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells at 1 uM by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X291DPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£ La Sapienza

Curated by ChEMBL
LigandPNGBDBM50308734(CHEMBL589812 | Isopropyl-2-methyl-5-[4-(methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-induced PGE2 production by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X291DPubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
Universit£ La Sapienza

Curated by ChEMBL
LigandPNGBDBM50308734(CHEMBL589812 | Isopropyl-2-methyl-5-[4-(methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX1-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X291DPubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£ La Sapienza

Curated by ChEMBL
LigandPNGBDBM50308734(CHEMBL589812 | Isopropyl-2-methyl-5-[4-(methylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of COX2-dependent PGE2 production in LPS-stimulated mouse J774 cells by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X291DPubMed