null

SMILES Fc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1

InChI Key InChIKey=GKIYCLAZFANGKD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309516   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniquesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0V17PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0V17PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0V17PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50309516(2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)copy SMILEScopy InChI
Affinity DataKi:  2.59E+3nMAssay Description:Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0V17PubMed