null
SMILES COc1ccc2n(C3CCC3)c(nc2c1)-c1nonc1N
InChI Key InChIKey=PEWIXJYBHWXEPB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50310471
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 940nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair