null
SMILES Cc1ccc2n(C3CCC3)c(nc2c1)-c1nonc1N
InChI Key InChIKey=WJBVKTYQLWGNGE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50310474
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of p70S6K assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of PKAalpha assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of GSK3beta assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of ROCK1 assessed as decrease in NADH absorbance at 340 nm in the presence ofMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Vertex Pharmaceuticals, Inc.
Curated by ChEMBL
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar
In DepthDetails