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SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(s1)-c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=AHXGZLJBINZPQZ-DYHNYNMBSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50311085   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311085((1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WMTPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311085((1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311085((1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311085((1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311085((1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfon...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed