null

SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(s1)-n1cc(Cl)cn1)C(O)=O

InChI Key InChIKey=GRSFKJZRDUZQPW-ONUMYQOESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50311088   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WMTPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant MMP9 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetCollagenase 3(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant MMP13 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WMTPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetStromelysin-1(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant MMP3 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS2WMTPubMed