null

SMILES Fc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F

InChI Key InChIKey=GHPCAIWYHJZRGR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50312156   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of EphB4 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312156(1-(2-fluoro-5-(trifluoromethyl)phenyl)-3-(3-(8-(py...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of Tie2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed