null

SMILES COc1ccc(Br)cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1

InChI Key InChIKey=OHZQTNDZRUYHEH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50312157   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of EphB4 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
CGI Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50312157(1-(5-bromo-2-methoxyphenyl)-3-(3-(8-(pyridin-4-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of Tie2 autophosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VM3PubMed