null

SMILES CN1C(=O)C(=Cc2ccc3OCOc3c2)N=C1NCCN

InChI Key InChIKey=AHHFGEKSWVBFGA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50312212   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CDK5/p25More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29023XHPubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universite£? de Rennes 1

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VHRPubMed
TargetDual specificity protein kinase CLK3(Mus musculus)
Universite£? de Rennes 1

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK3 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VHRPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VHRPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Universite£? de Rennes 1

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VHRPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Universite£? de Rennes 1

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VHRPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Universite£? de Rennes 1

Curated by ChEMBL
LigandPNGBDBM50312212((5Z)-5-[(1,3-benzodioxo-5-yl)methylene]-3-methyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant Pim1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2VHRPubMed