null
SMILES Fc1cccc(F)c1-n1ncc2c(Nc3cc(ccc3Cl)C(=O)NC3CC3)nncc12
InChI Key InChIKey=ZWVCUFJZBBAOFI-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50313107
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia
Curated by ChEMBL
University of Perugia
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia
Curated by ChEMBL
University of Perugia
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia
Curated by ChEMBL
University of Perugia
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Perugia
Curated by ChEMBL
University of Perugia
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair