null

SMILES Cc1cc(CN2CC(C2)C(O)=O)ccc1NC(=O)c1cc(ncn1)N(CC1CC1)C1CCCCC1

InChI Key InChIKey=PSYRPGKNBHSBJV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50313312   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313312(1-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Agonist activity at S1P1 receptor expressed in human U20S cells assessed as receptor internalization by green fluorescent protein reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313312(1-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)copy SMILEScopy InChI
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313312(1-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)copy SMILEScopy InChI
Affinity DataEC50:  236nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313312(1-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimi...)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed