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SMILES Cc1cc(O)ccc1NC(=O)c1cc(NC2CCCCC2)ncn1

InChI Key InChIKey=BGHQPXFERWTACA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50313325   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
MERCK SERONO SA

US Patent
LigandPNGBDBM50313325(6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)py...)copy SMILEScopy InChI
Affinity DataKi:  550nM ΔG°:  -7.93kcal/molepH: 7.4 T: 2°CAssay Description:Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 35S-GTPgammaS binding studies. Cells were suspended in 50 mM TRI...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993ZKUS Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313325(6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)py...)copy SMILEScopy InChI
Affinity DataEC50:  258nMAssay Description:Agonist activity at S1P5 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
MERCK SERONO SA

US Patent
LigandPNGBDBM50313325(6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)py...)copy SMILEScopy InChI
Affinity DataEC50:  1.16E+3nMAssay Description:Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313325(6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)py...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at S1P3 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SQKPubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
MERCK SERONO SA

US Patent
LigandPNGBDBM50313325(6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)py...)copy SMILEScopy InChI
Affinity DataEC50:  1.16E+3nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993ZKUS Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Merck Serono SA

Curated by ChEMBL
LigandPNGBDBM50313325(6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)py...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMpH: 7.4 T: 2°CAssay Description:Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H993ZKUS Patent