null

SMILES CN1C(=O)NC(=O)[C@@]11Cc2cc3ccc(CN4CC5(C)CC(=O)Nc6cccc4c56)nc3cc2C1

InChI Key InChIKey=BPFRJWCFOHDGJV-GEVKEYJPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315406   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50315406((4'S)-3'-methyl-2-((2a-methyl-4-oxo-2a,3,4,5-tetra...)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765FFZPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50315406((4'S)-3'-methyl-2-((2a-methyl-4-oxo-2a,3,4,5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765FFZPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50315406((4'S)-3'-methyl-2-((2a-methyl-4-oxo-2a,3,4,5-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765FFZPubMed