null

SMILES CC12CN(Cc3ccc4cc5C[C@]6(Cc5cc4n3)C(=O)Nc3ncccc63)c3cccc(NC(=O)C1)c23

InChI Key InChIKey=POPMFYTWOQSHIL-BDCODIICSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50315407   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50315407(2a-methyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro...)copy SMILEScopy InChI
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765FFZPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50315407(2a-methyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765FFZPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50315407(2a-methyl-1-(((R)-2'-oxo-1',2',6,8-tetrahydrospiro...)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765FFZPubMed