null
SMILES CC12CN(Cc3ccc4cc5C[C@]6(Cc5cc4n3)C(=O)Nc3ncccc63)c3cccc(NC(=O)C1)c23
InChI Key InChIKey=POPMFYTWOQSHIL-BDCODIICSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50315407
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co.
Curated by ChEMBL
Merck& Co.
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair