null

SMILES CN(C)CCc1ccc(Nc2nccc(n2)-c2c(nc3sccn23)-c2cccc(NC(=O)c3c(F)cccc3F)c2)cc1

InChI Key InChIKey=CDIOXDOXJQDENS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315895   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50315895(CHEMBL1090357 | N-(3-(5-(2-(4-(2-(dimethylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of ErbB2 intracellular phosphorylation in human N87 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908VTPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50315895(CHEMBL1090357 | N-(3-(5-(2-(4-(2-(dimethylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908VTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50315895(CHEMBL1090357 | N-(3-(5-(2-(4-(2-(dimethylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of EGFR intracellular phosphorylation in human A431 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908VTPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50315895(CHEMBL1090357 | N-(3-(5-(2-(4-(2-(dimethylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908VTPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50315895(CHEMBL1090357 | N-(3-(5-(2-(4-(2-(dimethylamino)et...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of ErbB2 by time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908VTPubMed