null

SMILES CNC[C@@H](O)CCN1c2ccccc2N(c2ccc(F)cc2F)S1(=O)=O

InChI Key InChIKey=JWVNRZQALLUPMN-ZDUSSCGKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319593   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319593((2S)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC32JRPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319593((2S)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC32JRPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319593((2S)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.19E+3nMAssay Description:Displacement of [3H]WIN35428 from human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC32JRPubMed