null

SMILES Fc1ccc(Oc2ccc(C#N)c(c2)C(F)(F)F)c(F)c1

InChI Key InChIKey=DZTBXKURUYOIDD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50319614   

TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 488nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed