null

SMILES CNc1nc(C)c(s1)-c1ccnc(Nc2ccc(cc2)N2CCN(CC2)C(C)=O)n1

InChI Key InChIKey=QLNAEPZXTGNWCX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50319615   

TargetAurora kinase B(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  9.70nMAssay Description:Inhibition of human recombinant Aurora B after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetAurora kinase A(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant Aurora A after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  297nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  448nMAssay Description:Inhibition of CDK9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  851nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Cyclacel Ltd.

Curated by ChEMBL
LigandPNGBDBM50319615(1-(4-(4-(4-(4-Methyl-2-(methylamino)thiazol-5-yl)p...)copy SMILEScopy InChI
Affinity DataKi:  1.08E+3nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930T9DPubMed