null

SMILES Oc1cc(F)ccc1-c1cc(-c2cccc(c2)N2CCNCC2)c(C#N)c(NC(=O)c2ccco2)n1

InChI Key InChIKey=UCWLBOAGWWOUDD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322299   

TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Displacement of [125I]metastin from human GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RHMPubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human GPR54 receptor assessed as inhibition of metastin-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RHMPubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50322299(CHEMBL1173643 | N-[3-Cyano-6-(4-fluoro-2-hydroxyph...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]metastin from rat GPR54 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6RHMPubMed