null

SMILES CCN1CCN(CCCOc2ccc(cc2C(F)(F)F)-c2cc3n(C)cnc3c(n2)C#N)CC1

InChI Key InChIKey=WRILSUPEKWTWKI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50323244   

TargetCathepsin S(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P85PubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of cathepsin S-mediated proteolytic cleavage of MHC2 associated invariant chain in mouse splenocytes assessed as accumulation of lip10 by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed
TargetCathepsin S(Mus musculus (Mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of human cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P85PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of cathepsin S in human JY cells assessed as accumulation of lip10 by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P85PubMed
TargetCathepsin L2(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin VMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P85PubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P85PubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 331nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P85PubMed
TargetCathepsin S(Homo sapiens (Human))
Merck Research laboratories

Curated by ChEMBL
LigandPNGBDBM50323244(6-(4-(3-(4-ethylpiperazin-1-yl)propoxy)-3-(trifluo...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028RR9PubMed